Attribut:Beschreibung-EN
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Data play an important role in medicine: Intensive care relies on monitors presenting and analysing real-time patient data, medical imaging has become a domain of massive data processing, diagnostics rely on laboratory data, and the importance of data is ever increasing: Wearable sensors, mobile communication devices and respective apps will produce data streams, which support preventive measures in healthy individuals or allow screening as a basis for data-based prevention of diseases. Last but not least: molecular biology (e.g. by gene sequencing and gene expression analysis) introduces new biomarkers, which enable new minimally-invasive diagnostics and approaches to tailoring treatments based on individual characteristics of patients (precision medicine) - which would never be possible without sophisticated processing of huge amounts of data. Medical decision making in general will be markedly influenced by data processing and data analytics. Thus, we can expect data driven medicine to gain momentum in the nearer future. This course offers a project-oriented, multidisciplinary introduction to the basics of data driven medicine. Orientation, fundamental concepts, and methodological approaches are provided by lectures. In addition, the participants will also form small interdisciplinary teams including students of computer science as well as medical students in order to plan and implement an own project, which targets prediction or decision support generated from medical data. +
'''Content''' The lecture "Data Warehouses for Medical Care and Research" teaches the basics of data acquisition, data access and data analysis of primary and secondary data sources in clinical trial research and care. Common methods and tools are introduced (electronic data capture, requirements analysis, design and validation of study databases, biomaterial databases, data dictionaries, standard operating procedures, automatic generation of reports, data mining in clinical application systems). During the exercises, the content from the lectures is applied to specific applications and practical scenarios. The respective software tools are first introduced in detail and demonstrated using complex examples. Subsequently, the students solve tasks on their own, as they are typically given to medical informatics specialists. The complete solution of the tasks is part of the self-study. <br/>'''Qualification Objectives''' Students will be able to explain fundamentals of data representation and data analysis of primary and secondary data sources, principles of data mining, data warehouses, knowledge management, (FAIR principles). Students will be able to perform queries on common databases. Students will be able to name / explain measures to ensure high quality data (based on FAIR principles). Students will be able to name / explain information processing requirements for clinical trials on EDC (Electronic Data Capture), e.g. from registries (German Cancer Registry). +